品牌	貨號	產(chǎn)品規(guī)格	價(jià)格(RMB)	庫存（上海）	北京	武漢	南京
源葉(MedMol)	S88807-5mg	98%	￥100.00元	6	-	-	-
源葉(MedMol)	S88807-10mg	98%	￥168.00元	7	-	-	-
源葉(MedMol)	S88807-25mg	98%	￥260.00元	10	-	-	-
源葉(MedMol)	S88807-50mg	98%	￥480.00元	3	-	-	-
源葉(MedMol)	S88807-100mg	98%	￥900.00元	6	-	-	-

產(chǎn)品介紹

Oxidopamine (6-OHDA) hydrochloride is an antagonist of the neurotransmitter dopamine. Oxidopamine hydrochloride is a widely used neurotoxin and selectively destroys dopaminergic neurons. Oxidopamine hydrochloride promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion. Oxidopamine hydrochloride can be used for the research of Parkinson’s disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome

產(chǎn)品描述：

靶點(diǎn)：

COX-2;IL-1β;Caspase-3;Caspase-8;Caspase-9

體內(nèi)研究：

Oxidopamine hydrochloride (5 μg/2 μL, unilaterally injected into the right striatum) induces degeneration of dopaminergic neurons in substantia nigra of rats

參考文獻(xiàn)：

1. Kang X, et al. Cyclooxygenase-2 contributes to oxidopamine-mediated neuronal inflammation and injury via the prostaglandin E2 receptor EP2 subtype. Sci Rep. 2017 Aug 25;7(1):9459. 2. Jin F, et al. Neuroprotective effect of resveratrol on 6-OHDA-induced Parkinson's disease in rats. Eur J Pharmacol. 2008 Dec 14;600(1-3):78-82. 3. Fujita H et al. Cell-permeable cAMP analog suppresses 6-hydroxydopamine-induced apoptosis in PC12 cells through the activation of the Akt pathway. Brain Res. 2006 Oct 3;1113(1):10-23. 4. Soto-Otero R et al. Autoxidation and neurotoxicity of 6-hydroxydopamine in the presence of some antioxidants: potential implication in relation to the pathogenesis of Parkinson's disease. J Neurochem. 2000 Apr;74(4):1605-12.

溶解性：

Soluble in DMSO、H2O

保存條件：

-20℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	4.863 ml	24.314 ml	48.629 ml
5 mM	0.973 ml	4.863 ml	9.726 ml
10 mM	0.486 ml	2.431 ml	4.863 ml
50 mM	0.097 ml	0.486 ml	0.973 ml

注意：

部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

參考文獻(xiàn)(2篇)

2. [IF=5.8] Peng Jiang et al."RVG29 Peptide-Modified Exosomes Loaded with Mir-133b Mediate the RhoA-ROCK Pathway to Improve Motor and Neurological Symptoms in Parkinson’s Disease."ACS Biomaterials Science & Engineering".2024;XXXX(XXX):XXX-XXX 1. [IF=5.8] Mengjiang Lu et al."Remodelling the inguinal adipose sensory system to switch on the furnace: Electroacupuncture stimulation induces brown adipose thermogenesis."DIABETES OBESITY & METABOLISM.2024 Jan;:

質(zhì)檢證書(COA)

輸入產(chǎn)品批號：

如何獲取質(zhì)檢證書(COA)?

請輸入貨號和一個(gè)與之匹配的批號。
例如:
批號：JS298415 貨號：S20001-25g
在貨品標(biāo)簽上如何找到貨號和批號?

摩爾濃度計(jì)算器

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

質(zhì)量

濃度

體積

分子摩爾量

計(jì)算重置

玖玖资源网站,爆乳久久久,日韩精品乱码久久久蜜桃,精品呦国产一区二区三区,国产伦高清一区二区三区,sese一区二区,午夜精品福利一区二区三区,三级黄色网站久久免费

6-Hydroxydopamine Hydrochloride 98%

6-Hydroxydopamine Hydrochloride