| 產品描述： | Histone Acetyltransferase Inhibitor II (compound 2c) is a potent, selective and cell permeable p300 histone acetyltransferase inhibitor, with an IC50 of 5 μM. Histone Acetyltransferase Inhibitor II shows anti-acetylase activity in mammalian cells |
| 靶點： |
IC50：5 μM (p300 histone acetyltransferase);EpigeneticReaderDomain;?HistoneAcetyltransferase |
| 體外研究： |
Histone Acetyltransferase Inhibitor II (20-40 μM) decreases the levels of H3 acetylation in HeLa-H2B-EYFP cells |
| 參考文獻： |
1. Costi R, et al. Cinnamoyl compounds as simple molecules that inhibit p300 histone acetyltransferase. J Med Chem. 2007 Apr 19;50(8):1973-7. Epub 2007 Mar 10. |
| 溶解性： |
Soluble in DMSO |
| 保存條件： |
-20℃ |
| 配置溶液濃度參考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.154 ml |
10.772 ml |
21.545 ml |
| 5 mM |
0.431 ml |
2.154 ml |
4.309 ml |
| 10 mM |
0.215 ml |
1.077 ml |
2.154 ml |
| 50 mM |
0.043 ml |
0.215 ml |
0.431 ml |
|
| 注意： |
部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。 |