產品描述: | Toltrazuril sulfone (Ponazuril) is a metabolite of Toltrazuril (HY-B0175), with antiprotozoal activity. Toltrazuril sulfone is a triazine anticoccidial that is developed to prevent coccidiosis in poultry |
靶點: |
Coccidia;Parasite |
體內研究: |
Toltrazuril sulfone (10-20 mg/kg; p.o.; daily; for 10 days) is effective in preventing and treating toxoplasmosis in mice Animal Model: Female CD-1 mice Dosage: 10 mg/kg, 20 mg/kg Administration: Oral administration, daily, for 10 days Result: Prevented and protected mice from toxoplasmosis. |
參考文獻: |
1. Sheila M Mitchell, et al. The effects of ponazuril on development of apicomplexans in vitro. J Eukaryot Microbiol. May-Jun 2005;52(3):231-5. 2. Sheila M Mitchell, et al. Efficacy of ponazuril in vitro and in preventing and treating Toxoplasma gondii infections in mice. J Parasitol. 2004 Jun;90(3):639-42. |
溶解性: |
Soluble in DMSO |
保存條件: |
2-8℃ |
配置溶液濃度參考: |
|
1mg |
5mg |
10mg |
1 mM |
2.186 ml |
10.932 ml |
21.864 ml |
5 mM |
0.437 ml |
2.186 ml |
4.373 ml |
10 mM |
0.219 ml |
1.093 ml |
2.186 ml |
50 mM |
0.044 ml |
0.219 ml |
0.437 ml |
|
注意: |
部分產品我司僅能提供部分信息,我司不保證所提供信息的權威性,僅供客戶參考交流研究之用。 |