| 產(chǎn)品描述： | Umbralisib R-enantiomer (TGR-1202 R-enantiomer) is a PI3Kδ inhibitor, which is the less active enantiomer of TGR-1202. |
| 靶點： |
PI3Kδ;PI3K |
| 體外研究： |
Umbralisib R-enantiomer (TGR-1202 R-enantiomer) (Formula A) exhibits a 50% inhibitory concentration (IC50) with respect to the δ type PI3-kinase that is at least 20-fold lower than the inhibitor's IC50 with respect to the rest of the other PI3K isoforms (i.e., a, β, and γ) |
| 參考文獻： |
1. Michael Weiss, et al. Combination of anti-cd20 antibody and pi3 kinase selective inhibitor. WO2014071125A1. |
| 溶解性： |
10 mM in DMSO |
| 保存條件： |
-20℃ |
| 配置溶液濃度參考： |
|
1mg |
5mg |
10mg |
| 1 mM |
1.75 ml |
8.748 ml |
17.496 ml |
| 5 mM |
0.35 ml |
1.75 ml |
3.499 ml |
| 10 mM |
0.175 ml |
0.875 ml |
1.75 ml |
| 50 mM |
0.035 ml |
0.175 ml |
0.35 ml |
|
| 注意： |
部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。 |
上海工商
危險品化學品經(jīng)營許可證（不帶存儲）
營業(yè)執(zhí)照(三證合一)
北京