品牌：源葉(MedMol)

產品編號：S83448 一鍵復制產品信息

CAS號：1477-68-5

分子式：C₉H₁₃NO₂.ClH

分子量：203.67

MDL：MFCD00012902

別名：2-甲氧基-4-(2-氨基乙基)苯酚;3-O-甲基多巴胺鹽酸鹽;3-甲氧基-4-羥基-β-苯乙胺鹽酸鹽,3-甲氧基多巴胺鹽酸鹽;甲基多巴胺鹽酸鹽;2-甲氧基-4-(2-氨基乙基)苯酚;甲基多巴胺鹽酸鹽/3-甲氧酪胺鹽酸鹽;3-甲氧基色胺鹽酸鹽;2-甲氧基-4-(2-氨基乙基)苯酚鹽酸鹽;3-甲;3-O-Methyldopanimehydrochloride;4-(2-Aminoethyl)-2-M

貨號	規格	價格	上海	北京	武漢	南京
S83448-100mg	98.5%	￥180.00 S83448-100mg ￥180.00 現貨	4 4	-	-	-
S83448-500mg	98.5%	￥450.00 S83448-500mg ￥450.00 現貨	4 4	-	-	-
S83448-1g	98.5%	￥750.00 S83448-1g ￥750.00 現貨	5 5	-	-	-

產品介紹

3-Methoxytyramine hydrochloride is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1).

產品描述：

3-Methoxytyramine hydrochloride is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1).

靶點：

Human Endogenous Metabolite;Others;?EndogenousMetabolite;?DrugMetabolite

體內研究：

The extracellular DA metabolite 3-Methoxytyramine hydrochloride (3-MT) induces significant behavioral activation in DDD mice. This activity however, is mostly presented as a set of disorganized abnormal movements that includes tremor, head bobbing, straub tail, grooming and abnormal orofacial movements rather than normal forward activity. No effect is observed when 3-Methoxytyramine hydrochloride is infused at doses below 9 μg, at 9 μg and higher doses 3-Methoxytyramine hydrochloride dose-dependently causes transient behavioral activation with a complex set of behaviors. In particular, transient hyperactivity and stereotypy, sniffing, grooming, rearing and mild abnormal involuntary movements (AIMs) at the level of limbs is observed after infusion of 9 μg of 3-Methoxytyramine hydrochloride. Similar behaviors are also observed after 18 μg of 3-Methoxytyramine hydrochloride with the additional appearance of tremor as well as oral and whole body AIMs

參考文獻：

1. Sotnikova TD, et al. The dopamine metabolite 3-methoxytyramine is a neuromodulator. PLoS One. 2010 Oct 18;5(10):e13452. 2. Guldberg HC, et al. Some observations on the estimation of 3-methoxytyramine in brain tissue. Br J Pharmacol. 1971 Aug;42(4):505-11.

溶解性：

DMSO : ≥ 100 mg/mL (490.99 mM)

保存條件：

-20℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	4.91 ml	24.55 ml	49.099 ml
5 mM	0.982 ml	4.91 ml	9.82 ml
10 mM	0.491 ml	2.455 ml	4.91 ml
50 mM	0.098 ml	0.491 ml	0.982 ml

注意：

部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻

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3-O-Methyldopamine Hydrochloride