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BAZEDOXIFENE ACETATE

    
99%

BAZEDOXIFENE ACETATE

源葉(MedMol)
S81422 一鍵復制產品信息
198481-33-3
C30H34N2O3.C2H4O2
530.655
醋酸巴多昔芬;醋酸巴多西芬;巴多昔芬醋酸鹽;醋酸巴澤昔芬;BAZEDOXIFENE ACETATE;1-(p-(2-(Hexahydro-1H-azepin-1-yl)ethoxy)benzyl)-2-(p-hydroxyphenyl)-3-methylindol-5-ol monoacetate (salt);1H-Indol-5-ol, 1-((4-(2-(hexahydro-1H-azepi
貨號 規格 價格 上海 北京 武漢 南京 購買數量
S81422-5mg 99% ¥410.00 1 - - -
S81422-10mg 99% ¥570.00 6 - - -
S81422-25mg 99% ¥850.00 5 - - -
S81422-50mg 99% ¥1160.00 4 - - -
S81422-100mg 99% ¥1660.00 5 - - -
產品介紹 參考文獻 質檢證書(COA) 摩爾濃度計算器 相關產品

產品介紹

Bazedoxifene acetate (TSE-424 acetate) is an oral, nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene acetate can be used for the research of osteoporosis. Bazedoxifene acetate also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer

產品描述: Bazedoxifene acetate (TSE-424 acetate) is an oral, nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene acetate can be used for the research of osteoporosis. Bazedoxifene acetate also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer
靶點: IC50: 26 nM (ERα), 99 nM (ERβ);EstrogenReceptor/ERR;?Estrogen/progestogenReceptor
體內研究: Bazedoxifene acetate (5 mg/kg; i.g.; daily, for 18 days) inhibits Capan-1 tumor growth in mouse model in vivo
參考文獻: 1. Barry S Komm, et al. Bazedoxifene acetate: a selective estrogen receptor modulator with improved selectivity. Endocrinology. 2005 Sep;146(9):3999-4008. 2. Xiaojuan Wu, et al. Bazedoxifene as a Novel GP130 Inhibitor for Pancreatic Cancer Therapy. Mol Cancer Ther. 2016 Nov; 15(11): 2609–2619.
溶解性: DMSO  :  ≥  100  mg/mL  (188.45  mM)    H2O  :  <  0.1  mg/mL  (insoluble)
保存條件: -20℃
配置溶液濃度參考:
1mg 5mg 10mg
1 mM 1.884 ml 9.422 ml 18.845 ml
5 mM 0.377 ml 1.884 ml 3.769 ml
10 mM 0.188 ml 0.942 ml 1.884 ml
50 mM 0.038 ml 0.188 ml 0.377 ml
注意: 部分產品我司僅能提供部分信息,我司不保證所提供信息的權威性,僅供客戶參考交流研究之用。

參考文獻

質檢證書(COA)

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批號:JS298415 貨號:S20001-25g
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摩爾濃度計算器

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

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