產(chǎn)品描述: | SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist. |
靶點: |
Serine/threonin kinase;Serine/threoninkinase |
體外研究: |
In HepG2 cells, SBC-115076 increases the uptake of Fluorescent Dil-LDL. |
體內(nèi)研究: |
In mice that are fed high fat diet, SBC-115076 (8 mg/kg) lowers cholesterol levels by 32%. |
參考文獻: |
1. Abdel-Meguid SS, et al. WO2014150326 A1. |
溶解性: |
soluble in DMSO |
保存條件: |
-20℃ |
配置溶液濃度參考: |
|
1mg |
5mg |
10mg |
1 mM |
1.895 ml |
9.477 ml |
18.953 ml |
5 mM |
0.379 ml |
1.895 ml |
3.791 ml |
10 mM |
0.19 ml |
0.948 ml |
1.895 ml |
50 mM |
0.038 ml |
0.19 ml |
0.379 ml |
|
注意: |
部分產(chǎn)品我司僅能提供部分信息,我司不保證所提供信息的權(quán)威性,僅供客戶參考交流研究之用。 |