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Oxibendazole

    
99%

methyl (5-propoxy-1H-benzo[d]imidazol-2-yl)carbamate

源葉(MedMol)
S80525 一鍵復制產品信息
20559-55-1
C12H15N3O3
249.27
奧苯噠唑;丙氧咪唑;丙氧苯咪唑;丙氧苯咪胺酯;Oxybendazole;methyl 5-(phenylsulfinyl)-1H-benzo[d]imidazol-2-ylcarbamate;Oxibendazole; SK&F-30310; SK&F30310; SK&F 30310; SKF-30310; SKF30310; SKF 30310. Anthelcide EQ; Loditac.
貨號 規格 價格 上海 北京 武漢 南京 購買數量
S80525-10mg 99% ¥80.00 貨期:2-3天 - - -
S80525-50mg 99% ¥160.00 9 - - -
S80525-250mg 99% ¥480.00 10 - - -
產品介紹 參考文獻 質檢證書(COA) 摩爾濃度計算器 相關產品

產品介紹

Oxibendazole is an effective benzimidazole anthelmintic and is against nema-tode infections. Oxibendazole can induces apoptosis and has anti-cancer and anti-inflammation activities

產品描述: Oxibendazole is an effective benzimidazole anthelmintic and is against nema-tode infections. Oxibendazole can induces apoptosis and has anti-cancer and anti-inflammation activities
靶點: Apoptosis;Parasite
體外研究: Cell proliferation decreased in both porcine trophectoder (pTr) and Porcine luminal epithelial (pLE) cells in response to Oxibendazole, and we determines that this is modulated through intracellular cell signal transduction. Phosphorylation of ERK1/2, P90RSK, and S6 are downregulated by exposure to a 200 nM dose of Oxibendazole in both types of cells, while the expression of phosphorylated JNK, AKT, and P70S6K is upregulated.
體內研究: The mean size of 22Rv1 tumors in nude mice treated with Oxibendazole (25 mg/kg/day) is 47.96% smaller than that of the control mice. Treatment with Oxibendazole increases the expression of microRNA-204 (miR-204).
參考文獻: 1. Hahyun Park , et al.Oxibendazole induces apoptotic cell death in proliferating porcine trophectoderm and uterine luminal epithelial cells via mitochondria-mediated calcium disruption and breakdown of mitochondrial membrane potential. Comp Biochem Physiol C Toxicol Pharmacol. 2019 Jun;220:9-19. 2. Qiaoli Chen, et al. Oxibendazole inhibits prostate cancer cell growth. Oncol Lett. 2018 Feb;15(2):2218-2226.
溶解性: Soluble  in  DMSO、H2O
保存條件: 2-8℃
配置溶液濃度參考:
1mg 5mg 10mg
1 mM 4.012 ml 20.059 ml 40.117 ml
5 mM 0.802 ml 4.012 ml 8.023 ml
10 mM 0.401 ml 2.006 ml 4.012 ml
50 mM 0.08 ml 0.401 ml 0.802 ml
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參考文獻

質檢證書(COA)

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摩爾濃度計算器

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

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