貨號	規格	價格	上海	北京	武漢	南京
S80479-1mg	≥98%	￥331.00 S80479-1mg ￥331.00 現貨	9 9	-	-	-
S80479-5mg	≥98%	￥835.00 S80479-5mg ￥835.00 現貨	10 10	-	-	-
S80479-10mg	≥98%	￥1420.00 S80479-10mg ￥1420.00 現貨	8 8	-	-	-
S80479-25mg	≥98%	￥3022.00 S80479-25mg ￥3022.00 現貨	8 8	-	-	-
S80479-50mg	≥98%	￥5146.00 S80479-50mg ￥5146.00 現貨	6 6	-	-	-
S80479-100mg	≥98%	￥8755.00 S80479-100mg ￥8755.00 現貨	5 5	-	-	-

大包裝詢價收藏產品

加入購物車

產品介紹

NCT-501 is a potent and selective theophylline-based inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), inhibits hALDH1A1 with IC50 of 40 nM, typically shows better selectivity over other ALDH isozymes and other dehydrogenases (hALDH1B1, hALDH3A1, and hALDH2, IC50 >57 μM).

產品描述：

靶點：

IC50: 40 nM (hALDH1A1);Dehydrogenase

體內研究：

NCT-501 (100 μg/animal; i.t.; every alternate day for 20 days) shows a 78% inhibition in tumor growth in Cal-27 CisR derived xenografts. Animal Model: 5-6 weeks old male Hsd: Athymic Nude-Foxn1nu (immuno-deficient-mice bearing Cal-27 CisR cells) Dosage: 100μg/animal Administration: Intra-tumorally (i.t); every alternate day for 20 days Result: Showed a 78% inhibition in tumor growth in Cal-27 CisR derived xenografts.

參考文獻：

1. Kulsum S et al. Cancer stem cell mediated acquired chemoresistance in head and neck cancer can be abrogated by Aldehydedehydrogenase 1 A1 inhibition. Mol Carcinog. 2016 Jul 6. 2. Yang SM, et al. Discovery of NCT-501, a Potent and Selective Theophylline-Based Inhibitor of Aldehyde Dehydrogenase 1A1(ALDH1A1). J Med Chem. 2015 Aug 13;58(15):5967-5978.

溶解性：

Soluble in DMSO

保存條件：

-20°C

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	2.401 ml	12.004 ml	24.009 ml
5 mM	0.48 ml	2.401 ml	4.802 ml
10 mM	0.24 ml	1.2 ml	2.401 ml
50 mM	0.048 ml	0.24 ml	0.48 ml

注意：

部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻

質檢證書(COA)

輸入產品批號：

如何獲取質檢證書(COA)?

請輸入貨號和一個與之匹配的批號。
例如:
批號：JS298415 貨號：S20001-25g
在貨品標簽上如何找到貨號和批號?

摩爾濃度計算器

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

質量

濃度

體積

分子摩爾量

計算重置

玖玖资源网站,爆乳久久久,日韩精品乱码久久久蜜桃,精品呦国产一区二区三区,国产伦高清一区二区三区,sese一区二区,午夜精品福利一区二区三区,三级黄色网站久久免费