產品描述: | IRBP (1-20), human TFA 包含 H-2b 單倍型的主要表位。IRBP (1-20), human TFA 誘導H-2b 小鼠實驗性自身免疫性葡萄膜視網膜炎 (EAU)。 |
體內研究: |
IRBP (1-20), human TFA induces EAU. For determination of proliferative and cytokine responses, lymph node and spleen cells are collected 21 days after immunization and are stimulated in culture with the appropriate antigen. Cells of C57BL/6 mice and 129/J mice immunized with IRBP (1-20), human TFA proliferated in response to the peptide. |
參考文獻: |
1. Avichezer D, et al. Residues 1-20 of IRBP and whole IRBP elicit different uveitogenic and immunological responses in interferon gamma deficient mice. Exp Eye Res. 2000;71(2):111‐118.
2. Avichezer D, Silver PB, Chan CC, Wiggert B, Caspi RR. Identification of a new epitope of human IRBP that induces autoimmune uveoretinitis in mice of the H-2b haplotype. Invest Ophthalmol Vis Sci. 2000;41(1):127‐131. |
溶解性: |
soluble in DMSO |
保存條件: |
-20℃ |
配置溶液濃度參考: |
|
1mg |
5mg |
10mg |
1 mM |
0.433 ml |
2.166 ml |
4.332 ml |
5 mM |
0.087 ml |
0.433 ml |
0.866 ml |
10 mM |
0.043 ml |
0.217 ml |
0.433 ml |
50 mM |
0.009 ml |
0.043 ml |
0.087 ml |
|
注意: |
部分產品我司僅能提供部分信息,我司不保證所提供信息的權威性,僅供客戶參考交流研究之用。 |