| 產品描述： | Stafia-1 is a potent STAT5a inhibitor (Ki=10.9 μM, IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members |
| 靶點： |
STAT5a:10.9 μM (Ki);STAT5a:22.2 μM (IC50);STAT |
| 體外研究： |
Stafia-1 shows at least 9-fold selectivity over STAT5b and higher selectivity against other STAT family members. |
| 參考文獻： |
1. Natarajan K, et al. Stafia-1: a STAT5a-Selective Inhibitor Developed via Docking-Based Screening of in Silico O-Phosphorylated Fragments. Chemistry. 2020;26(1):148-154. |
| 溶解性： |
Soluble in DMSO |
| 保存條件： |
-20℃ |
| 配置溶液濃度參考： |
|
1mg |
5mg |
10mg |
| 1 mM |
1.975 ml |
9.873 ml |
19.746 ml |
| 5 mM |
0.395 ml |
1.975 ml |
3.949 ml |
| 10 mM |
0.197 ml |
0.987 ml |
1.975 ml |
| 50 mM |
0.039 ml |
0.197 ml |
0.395 ml |
|
| 注意： |
部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。 |
上海工商
危險品化學品經營許可證（不帶存儲）
營業執照(三證合一)
北京