品牌：源葉

產(chǎn)品編號(hào)：B25905 一鍵復(fù)制產(chǎn)品信息

CAS號(hào)：220620-09-7

分子式：C₂₉H₃₉N₅O₈

分子量：585.65

MDL：MFCD00935753

別名：(4S,4aS,5aR,12aS)-4,7-雙(二甲氨基)-9-[(叔丁基氨基)乙酰胺基]-3,10,12,12a-四羥基-1,11-二氧代-1,4,4a,5,5a,6,11,12a-八氫并四苯-2-甲酰胺

貨號(hào)	規(guī)格	價(jià)格	上海	北京	武漢	南京	購(gòu)買(mǎi)數(shù)量
B25905-20mg	分析標(biāo)準(zhǔn)品,HPLC≥98%	￥360.00 B25905-20mg ￥360.00 現(xiàn)貨	7 7 7	2	2	3

產(chǎn)品介紹

Tigecycline (GAR-936) 是一種廣譜的甘氨酰環(huán)素抗生素。Tigecycline 對(duì) E. coli (MG1655 菌株) 的平均抑制濃度 (MIC) 約為 125 ng/ mL。對(duì) Acinetobacter baumannii (A. baumannii) 的 MIC₅₀ 和 MIC₉₀ 分別為 1 和 2 mg/L。

熔點(diǎn)：	164-166°C
沸點(diǎn)：	890.922°C at 760 mmHg
外觀：	Orange powder
溶解性：	DMSO : 150 mg/mL (256.13 mM; Need ultrasonic) H2O : 8.33 mg/mL (14.22 mM; ultrasonic and warming and heat to 60°C)
儲(chǔ)存條件：	2-8℃
注意：	部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶(hù)參考交流研究之用。

參考文獻(xiàn)(10篇)

10. [IF=6.7] Mengxiang Zheng et al."Curcumin reverses high-level tigecycline resistance mediated by different mechanisms in Gram-negative bacteria."PHYTOMEDICINE.2024 Dec;:156319 9. [IF=3.8] Juan Wang et al."Research note: Prevalence and genetic characteristics of pathogenic E. coli isolates from domestic pigeons in central China."POULTRY SCIENCE.2025 Feb;104:104705 8. [IF=5] Fulei Li et al."Inosine reverses multidrug resistance in Gram-negative bacteria carrying mobilized RND-type efflux pump gene cluster tmexCD-toprJ."mSystems. 7. [IF=6.4] Yang# Jindian et al."Repurposing harmaline as a novel approach to reverse tmexCD1-toprJ1-mediated tigecycline resistance against klebsiella pneumoniae infections."Microbial Cell Factories".2024 Dec;23(1):1-17 6. [IF=7.9] Xia Xiao et al."Gramine sensitizes Klebsiella pneumoniae to tigecycline killing."PHYTOMEDICINE".2024 Feb;:155421

5. [IF=3.9] Jie Wu et al."In vitro Antimicrobial Activity and Dose Optimization of Eravacycline and Other Tetracycline Derivatives Against Levofloxacin-Non-Susceptible and/or Trimethoprim-Sulfamethoxazole-Resistant Stenotrophomonas maltophilia."Infection and Drug Resi 4. [IF=5.988] Wei Lu et al."An LC-MS/MS method for the simultaneous determination of 18 antibacterial drugs in human plasma and its application in therapeutic drug monitoring."Frontiers in Pharmacology.2022 Nov 8;13:1044234 3. [IF=5.882] Zi-Jian Zheng et al."MALDI-TOF MS for rapid detection and differentiation between Tet(X)-producers and non-Tet(X)-producing tetracycline-resistant Gram-negative bacteria."Virulence. 2022;13(1):77-88 2. [IF=4.003] Hui Zhang et al.In vitro and in vivo Activity of Combinations of Polymyxin B with Other Antimicrobials Against Carbapenem-Resistant Acinetobacter baumannii.Infect Drug Resist. 2021 Nov;14:4657-4666 1. 馬霖孫加琳李恩澤等. LC-MS/MS法同時(shí)測(cè)定人血漿中伏立康唑和替加環(huán)素的濃度[J]. 中國(guó)臨床藥理學(xué)雜志 2019 035(024):3237-3240.

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