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三七皂苷R1

    
分析標準品,HPLC≥98%

Notoginsenoside R1

源葉
B21099 一鍵復制產品信息
80418-24-2
C47H80O18
933.13
MFCD00210535
貨號 規格 價格 上海 北京 武漢 南京 購買數量
B21099-20mg 分析標準品,HPLC≥98% ¥200.00 >10 4 6 4
B21099-200mg 分析標準品,HPLC≥98% ¥1200.00 >10 - - -
產品介紹 參考文獻(82篇) 質檢證書(COA) 摩爾濃度計算器 相關產品

產品介紹

 Notoginsenoside R1 (Sanchinoside R1),是一種從 P. notoginseng 中分離出來的皂苷。 Notoginsenoside R1 具有抗氧化,抗炎,抗血管生成和抗凋亡的活性。Notoginsenoside R1 可提供抗缺血/再灌注 (I/R) 損傷的心臟保護作用。Notoginsenoside R1 還可以提供神經保護作用。

熔點: 215-217°C
沸點: 1010.5 °C at 760 mmHg
比旋光度: (c, 1.0 in MeOH)+15
外觀: 白色粉末
溶解性: DMSO  :  100  mg/mL  (107.17  mM;  Need  ultrasonic)
敏感性: 易吸潮
儲存條件: 2-8℃
注意: 部分產品我司僅能提供部分信息,我司不保證所提供信息的權威性,僅供客戶參考交流研究之用。

參考文獻(82篇)

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[IF=6.1] Yuan Li et al."Notoginsenoside R1 decreases intraplaque neovascularization by governing pericyte-endothelial cell communication via Ang1/Tie2 axis in atherosclerosis."PHYTOTHERAPY RESEARCH.2024 Jun;: 72. [IF=6.8] Yun Zhao et al."The plant extract PNS mitigates atherosclerosis via promoting Nrf2-mediated inhibition of ferroptosis through reducing USP2-mediated Keap1 deubiquitination."BRITISH JOURNAL OF PHARMACOLOGY.2024 Sep;: 71. [IF=3.3] Rong Liu et al."Characterization of a Xylosyltransferase from Panax notoginseng Catalyzing Ginsenoside 2′-O Glycosylation in the Biosynthesis of Notoginsenosides."JOURNAL OF NATURAL PRODUCTS.2024;XXXX(XXX):XXX-XXX 70. [IF=4.8] Liying Ma et al."Notoginsenoside R1 Ameliorate High-Fat-Diet and Vitamin D3-Induced Atherosclerosis via Alleviating Inflammatory Response, Inhibiting Endothelial Dysfunction, and Regulating Gut Microbiota."Drug Design Development and Therapy.10.2147/DDDT. 69. 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[IF=3.5] Zhu Cun et al."Integrated metabolome and transcriptome analysis reveals the regulatory mechanism of low nitrogen-driven biosynthesis of saponins and flavonoids in Panax notoginseng."GENE.2024 Jan;:148163 64. [IF=5.4] Yingqiu Shi et al."Effective constituents and protective effect of Mudan granules against Schwann cell injury."JOURNAL OF ETHNOPHARMACOLOGY.2024 Apr;323:117692 63. [IF=3.4] Xiaonan Wang et al."Notoginsenoside R1 ameliorates the inflammation induced by amyloid?β by suppressing SphK1?mediated NF?κB activation in PC12 cells."Molecular Medicine Reports.2024 Jan;29(1):1-11 62. [IF=3.7] Xiaoxian Pei et al."Notoginsenoside R1 attenuates brain injury in rats with traumatic brain injury: Possible mediation of apoptosis via ERK1/2 signaling pathway."PLoS One.2023 Dec;18(12):e0295903 61. [IF=4.8] Guozhuang Zhang et al."Rhizosphere effects on the microbial community: Specificity and conservatism across geographically disjunct Panax species."APPLIED SOIL ECOLOGY.2023 Dec;192:105075 60. [IF=7.9] Zhang Guozhuang et al."Modules in robust but low-efficiency phyllosphere fungal networks drive saponin accumulation in leaves of different Panax species."Environmental Microbiome.2023 Dec;18(1):1-15 59. [IF=4.546] Xu Ying et al."Panax notoginseng saponins inhibits NLRP3 inflammasome-mediated pyroptosis by downregulating lncRNA-ANRIL in cardiorenal syndrome type 4."Chinese Medicine.2023 Dec;18(1):1-13 58. [IF=6.388] He Zhang et al."Prevention effect of total ginsenosides and ginseng extract from Panax ginseng on cyclophosphamide-induced immunosuppression in mice."PHYTOTHERAPY RESEARCH.2023 Apr;: 57. [IF=4.927] Junchen Liu et al."Anti-Inflammatory Activity of Panax notoginseng Flower Saponins Quantified Using LC/MS/MS."MOLECULES.2023 Jan;28(5):2416 56. [IF=6.449] Na Li et al."β-Xylosidase mutant immobilization on UiO-66-NH2 for continuous production of ginsenoside Rg1 and selective production of furfural from notoginsenoside R1."INDUSTRIAL CROPS AND PRODUCTS.2023 Jul;197:116563 55. [IF=6.656] Linying Xia et al."Panax notoginseng saponins normalises tumour blood vessels by inhibiting EphA2 gene expression to modulate the tumour microenvironment of breast cancer."PHYTOMEDICINE.2023 Mar;:154787 54. [IF=3.061] Zhu Cun et al."High nitrogen inhibits biomass and saponins accumulation in a medicinal plant Panax notoginseng."PeerJ.2023 Feb;11:e14933 53. [IF=3.945] Linlin Su et al."Development of SSR markers on the basis of the Panax notoginseng transcriptome for agronomic and biochemical trait association analyses."Journal of Applied Research on Medicinal and Aromatic Plants.2023 Apr;34:100475 52. [IF=14.026] Junyun Cheng et al."High-throughput transcriptional profiling of perturbations by Panax ginseng saponins and Panax notoginseng saponins using TCM-seq."Journal of Pharmaceutical Analysis.2023 Feb;: 51. [IF=4.927] Hong-Ping Wang et al."Comprehensive Identification of Ginsenosides in the Roots and Rhizomes of Panax ginseng Based on Their Molecular Features-Oriented Precursor Ions Selection and Targeted MS/MS Analysis."MOLECULES.2023 Jan;28(3):941 50. [IF=4.036] Hongping Wang et al."Improving natural products identification through molecular features-oriented precursor ion selection and targeted MS/MS analysis: a case study of Zhi-Ke-Yang-Yin capsule."RSC Advances.2022 Nov;12(51):33340-33347 49. [IF=0] Hong Kan et al."Identification of anti-inflammatory components in Panax ginseng of Sijunzi Decoction based on spectrum-effect relationship."Chinese Herbal Medicines.2022 Oct;: 48. [IF=5.988] Mengwen Huang et al."Discovering the potential active ingredients of Qi-Yu-San-Long decoction for anti-oxidation, inhibition of non-small cell lung cancer based on the spectrum-effect relationship combined with chemometric methods.."Frontiers in Pharmacol 47. [IF=2.893] Zhong Peng et al."Characterization of a novel thermophilic beta-glucosidase from Thermotoga sp. and its application in the transformation of notoginsenoside R1."3 Biotech.2022 Nov;12(11):1-14 46. [IF=6.449] Na Li et al."Enhanced conversion and extraction of ginsenoside Rg1 from Panax notoginseng using β-xylosidase mutants and an endoxylanase."INDUSTRIAL CROPS AND PRODUCTS.2022 Nov;187:115514 45. [IF=3.318] Hongda Sheng et al."Identification of bioactive ingredients from Babaodan using UPLC-QTOF-MS analysis combined with network pharmacology guided bioassays."JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES.2022 Aug;120 44. [IF=5.811] He Zhang et al."Prevention Effect of Protopanaxadiol-Type Saponins Saponins and Protopanaxatriol-Type Saponins on Myelosuppression Mice Induced by Cyclophosphamide.."Frontiers in Pharmacology. 2022 Apr;13:845034-845034 43. [IF=3.373] Yu Yao et al."UPLC–MS/MS method for the determination of the herb composition of Tangshen formula and the in vivo pharmacokinetics of its metabolites in rat plasma."Phytochemical Analysis. 2021 Dec 14 42. [IF=1.978] Wang Rong-rong et al."Acute Developmental Toxicity of Panax notoginseng in Zebrafish Larvae."Chin J Integr Med. 2022 Jan;:1-8 41. [IF=4.411] Xuanming Zhang et al.Region-Specific Biomarkers and Their Mechanisms in the Treatment of Lung Adenocarcinoma: A Study of Panax quinquefolius from Wendeng, China.Molecules. 2021 Jan;26(22):6829 40. [IF=3.199] Li Yuan et al."In Vitro Anti-hepatoma Activities of Notoginsenoside R1 Through Downregulation of Tumor Promoter miR-21."Digest Dis Sci. 2020 May;65(5):1364-1375 39. [IF=3.205] Jie Tang et al."Metabolite profiling of Shuganzhi tablets in rats and pharmacokinetics study of four bioactive compounds with liquid chromatography combined with electrospray ionization tandem mass spectrometry."J Chromatogr B. 2021 Aug;1179:122827 38. [IF=3.503] Jiajia Dong et al."Comparative pharmacokinetic analysis of raw and steamed Panax notoginseng roots in rats by UPLC-MS/MS for simultaneously quantifying seven saponins."Pharm Biol. 2021;59(1):653-661 37. [IF=3.645] Mengmeng Jia et al."UHPLC coupled with mass spectrometry and chemometric analysis of Kang-Ai injection based on the chemical characterization, simultaneous quantification, and relative quantification of 47 herbal alkaloids and saponins."J Sep Sci. 2020 Ju 36. [IF=3.69] Tianyuan Yu et al."Anti-inflammation effect of Qingchang suppository in ulcerative colitis through JAK2/STAT3 signaling pathway in vitro and in vivo."J Ethnopharmacol. 2021 Feb;266:113442 35. [IF=3.882] Kunpeng Yin et al."Lanthanide Metal–Organic Framework-Based Fluorescent Sensor Arrays to Discriminate and Quantify Ingredients of Natural Medicine."Langmuir. 2021;37(17):5321–5328 34. [IF=3.932] Bo Cao et al."Protective effects of notoginsenoside R1 on acute lung injury in rats with sepsis."Ann Transl Med. 2021 Jun; 9(12): 996 33. [IF=3.935] Ruimei Lin et al."Global identification and determination of the major constituents in Kai-Xin-San by ultra-performance liquid chromatography-quadrupole-Orbitrap mass spectrometry and gas chromatography-mass spectrometry."J Pharmaceut Biomed. 2021 Nov;206 32. [IF=4.142] Wang Chenxi et al."Rapid discovery of potential ADR compounds from injection of total saponins from Panax notoginseng using data-independent acquisition untargeted metabolomics."Analytical And Bioanalytical Chemistry. 2021 Oct 26 31. [IF=4.162] Weixin Hou et al."The Jieduan-Niwan (JDNW) Formula Ameliorates Hepatocyte Apoptosis: A Study of the Inhibition of E2F1-Mediated Apoptosis Signaling Pathways in Acute-on-Chronic Liver Failure (ACLF) Using Rats."Drug Des Dev Ther. 2021; 15: 3845–3862 30. [IF=4.36] Yongshen Ren et al."Anticoagulant active ingredients identification of total saponin extraction of different Panax medicinal plants based on grey relational analysis combined with UPLC-MS and molecular docking."J Ethnopharmacol. 2020 Oct;260:112955 29. [IF=4.759] Yi Zhang et al."Screening of inhibitors against histone demethylation jumonji domain-containing protein 3 by capillary electrophoresis."J Chromatogr A. 2020 Feb;1613:460625 28. [IF=5.34] Gui Zhou et al."Effects of Qing Chang Suppository Powder and its Ingredients on IL-17 Signal Pathway in HT-29 Cells and DSS-induced Mice."Phytomedicine. 2021 Jul;87:153573 27. [IF=5.81] Xiaoyu Liu et al."Geniposide Combined With Notoginsenoside R1 Attenuates Inflammation and Apoptosis in Atherosclerosis via the AMPK/mTOR/Nrf2 Signaling Pathway."Front Pharmacol. 2021; 12: 687394 26. [IF=0] Dingkun Gui et al."Notoginsenoside R1 Ameliorates Podocyte Adhesion Under Diabetic Condition Through α3β1 Integrin Upregulation in Vitro and in Vivo."Cell Physiol Biochem. 2014;34(6):1849-1862 25. [IF=3.575] Ting Wang et al."Notoginsenoside R1 stimulates osteogenic function in primary osteoblasts via estrogen receptor signaling."Biochem Bioph Res Co. 2015 Oct;466:232 24. [IF=4.213] Qiangyuan Fan et al."Improved oral bioavailability of notoginsenoside R1 with sodium glycocholate-mediated liposomes: Preparation by supercritical fluid technology and evaluation in vitro and in vivo."Int J Pharmaceut. 2018 Dec;552:360 23. 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Ting Wang, Daqian Wan, Lei Shao, Jiezhi Dai, Chaoyin Jiang, Notoginsenoside R1 stimulates osteogenic function in primary osteoblasts via estrogen receptor signaling, Biochemical and Biophysical Research Communications, Volume 466, Issue 2, 2015, Pages 232- 18. 樂世俊,王文曉,高歡,任繼國,付瑞嘉,李佳佳,陳艷琰,唐于平.HPLC同時測定不同廠家丹七片中多個有效成分的含量[J].藥物分析雜志,2020,40(12):2236-2243. 17. 杜靜. 冠突散囊菌對中藥材三七成分的轉化及機理研究[D].貴州師范大學,2020. 16. 吳雨佳, 王令充, 張雯,等. 生物黏附性三七總皂苷-白及多糖-海藻酸鈉復合微球的制備及表征[J]. 中草藥, 2019, v.50;No.655(20):49-56. 15. 張永 陳旭 丁越 等. 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摩爾濃度計算器

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