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川陳皮素 HPLC≥98%

Nobiletin

源葉
B20199
478-01-3
C21H22O8
402.39
MFCD03273560
品牌 貨號(hào) 產(chǎn)品規(guī)格 價(jià)格(RMB) 庫(kù)存(上海) 北京 武漢 南京 購(gòu)買數(shù)量
源葉 B20199-20mg HPLC≥98% ¥300.00元 >10 3 1 5
源葉 B20199-500mg HPLC≥98% ¥2660.00元 >10 - - -
源葉 B20199-1g HPLC≥98% ¥4800.00元 2 - - -
產(chǎn)品介紹 參考文獻(xiàn)(92篇) 質(zhì)檢證書(COA) 摩爾濃度計(jì)算器 相關(guān)產(chǎn)品

產(chǎn)品介紹

熔點(diǎn): 137-138°C
沸點(diǎn): 587.9°Cat760mmHg
外觀: 無(wú)色晶體
溶解性: 可溶于DMSO、氯仿和甲醇的混合溶劑,微溶于水和乙醚,不溶于石油醚。
敏感性: 對(duì)熱敏感
儲(chǔ)存條件: -20℃
注意: 部分產(chǎn)品我司僅能提供部分信息,我司不保證所提供信息的權(quán)威性,僅供客戶參考交流研究之用。

參考文獻(xiàn)(92篇)

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[IF=8.5] Yunyi Chen et al."Hepatoprotective potential of four fruit extracts rich in different structural flavonoids against alcohol-induced liver injury via gut microbiota-liver axis."FOOD CHEMISTRY.2024 Dec;460:140460 78. [IF=4.9] Chenning Zhao et al."Integrated Metabolomic–Transcriptomic Analyses of Flavonoid Accumulation in Citrus Fruit under Exogenous Melatonin Treatment."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2024 Jan;25(12):6632 77. [IF=7] Xin Huang et al."The effects of core microorganism community on flavor compounds and active substances during the aging process of Citri Reticulatae Pericarpium."FOOD RESEARCH INTERNATIONAL.2024 Jun;:114707 76. [IF=4.3] Nawei Zhang et al."Factors affecting the formation of delayed bitterness in sweet orange (Citrus sinensis (L.) Osbeck) juice."JOURNAL OF FOOD COMPOSITION AND ANALYSIS".2024 Aug;132:106298 75. [IF=5] Zhang Zhihong et al."Synergistic modification of hot-melt extrusion and nobiletin on the multi-scale structures, interactions, thermal properties, and in vitro digestibility of rice starch."Frontiers in Nutrition".2024 May;11: 74. [IF=5.4] Yanchi Liu et al."Nobiletin enhances the antifungal activity of eugenol nanoemulsion against Penicillium italicum in both in vitro and in vivo settings."INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY".2024 Aug;420:110769 73. [IF=6.1] Jingqi Yang et al."Highly Effective Nobiletin–MPN in Yeast Microcapsules for Targeted Modulation of Oxidative Stress, NLRP3 Inflammasome Activation, and Immune Responses in Ulcerative Colitis."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY".2024;XXXX(XXX):XXX 72. [IF=3.9] Junjie Shi et al."Evaluation of chemical components and quality in Xinhui Chenpi (Citrus reticulata ‘Chachi’) with two different storage times by GC–MS and UPLC."Food Science & Nutrition".2024 Apr;: 71. [IF=4.6] Wang Hong-Ping et al."Comprehensive identifying flavonoids in Citri Reticulatae Pericarpium using a novel strategy based on precursor ions locked and targeted MS/MS analysis."Scientific Reports".2024 Apr;14(1):1-9 70. [IF=2.7] Tong Wang et al."Flavonoids from Citrus reticulata: Inhibitory activity against pathogenic fungi and biocontrol potential."PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY".2024 May;131:102250 69. [IF=6] Jianping Jiang et al."The optimization of extraction process on Quzhou Fructus Aurantii flavonoids with natural deep eutectic solvents: A comparative study between orthogonal analysis and genetic neural network."LWT-FOOD SCIENCE AND TECHNOLOGY".2024 Apr;1 68. [IF=8.4] Xiaonan Zhang et al."Antisolvent precipitation for the synergistic preparation of ultrafine particles of nobiletin under ultrasonication-homogenization and evaluation of the inhibitory effects of α-glucosidase and porcine pancreatic lipase in vitro."ULTRA 67. [IF=8.8] Shiheng Chen et al."Short-term steaming during processing impacts the quality of Citri Reticulatae ‘Chachi’ peel."FOOD CHEMISTRY".2024 Jul;447:138964 66. [IF=3.4] Yanhua Jiang et al."Network pharmacology combined with lipidomics to reveal the regulatory effects and mechanisms of Kangzao granules in the hypothalamus of rats with central precocious puberty."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS".2024 May; 65. [IF=5.2] Dan Wu et al."Optimizing the Solvent Selection of the Ultrasound-Assisted Extraction of Sea Buckthorn (Hippophae rhamnoides L.) Pomace: Phenolic Profiles and Antioxidant Activity."Foods".2024 Jan;13(3):482 64. [IF=8.8] Yuan Liu et al."Flavor characterization of Citri Reticulatae Pericarpium (Citrus reticulata ‘Chachiensis’) with different aging years via sensory and metabolomic approaches."FOOD CHEMISTRY.2024 Jun;443:138616 63. [IF=6.1] Chaowen Fan et al."Nobiletin Ameliorates Hepatic Lipid Deposition, Oxidative Stress, and Inflammation by Mechanisms That Involve the Nrf2/NF-κB Axis in Nonalcoholic Fatty Liver Disease."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2023;XXXX(XXX):XXX-XXX 62. [IF=5.6] Hai He et al."In-situ complexation of rice starch and nobiletin by extrusion alleviates ulcerative colitis and modulates dysbiosis of intestinal flora in C57BL/6 mice."Journal of Functional Foods.2023 Nov;110:105875 61. [IF=5] Tianzhu Guan et al."In vitro and in silico perspectives on the activation of antioxidant responsive element by citrus-derived flavonoids."Frontiers in Nutrition.2023; 10: 1257172 60. [IF=1.7] Zhouyi Zhang et al."Revealing the differences in phenolics in different parts of Taraxacum mongolicum using UPLC-MS/MS."Phytochemistry Letters.2023 Aug;56:13 59. [IF=9.336] Xiaonan Zhang et al."Anti-solvent precipitation for the preparation of nobiletin nano-particles under ultrasonication-cis/reverse homogenization."ULTRASONICS SONOCHEMISTRY.2023 Jun;96:106433 58. [IF=5.895] Jiebiao Chen et al."Polymethoxyflavone–Enriched Fraction from Ougan (Citrus reticulata cv. Suavissima) Attenuated Diabetes and Modulated Gut Microbiota in Diabetic KK-Ay Mice."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2023;XXXX(XXX):XXX-XXX 57. [IF=6.317] Lufang Chen et al."3D-QSAR studies on the structure–bitterness analysis of citrus flavonoids."Food & Function.2023 Apr;: 56. [IF=4.927] Zunli Ke et al."Nobiletin Intake Attenuates Hepatic Lipid Profiling and Oxidative Stress in HFD-Induced Nonalcoholic-Fatty-Liver-Disease Mice."MOLECULES.2023 Jan;28(6):2570 55. [IF=6.443] Yi Zhang et al."Novel application of HS-GC-IMS for characteristic fingerprints and flavor compound variations in citrus reticulatae pericarpium during storage with different Aspergillus niger fermentation."Food Chemistry-X.2023 Jun;18:100653 54. [IF=9.221] Wei Lan et al."Rapid visual discrimination of Citri Reticulatae Pericarpium from different origins by fluorescent sensors based on aluminum ions and Ag nanoclusters."SENSORS AND ACTUATORS B-CHEMICAL.2023 Apr;380:133329 53. [IF=1.698] Jinyan Wu et al."Chemical Identification and Antioxidant Screening of Bufei Yishen Formula using an Offline DPPH Ultrahigh-Performance Liquid Chromatography Q-Extractive Orbitrap MS/MS."International Journal of Analytical Chemistry.2022 Oct 15;2022:142380 52. [IF=4.132] Jintao Lü et al."Network Analysis of the Herb–Drug Interactions of Citrus Herbs Inspired by the “Grapefruit Juice Effect”."ACS Omega.2022;7(40):35911–35923 51. [IF=5.168] Pan Wang et al."Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay."CHEMICO-BIOLOGICAL INTERACTIONS.2022 Nov;367:110199 50. [IF=6.208] Pan Wang et al."Discovery of Flavonoids as Novel Inhibitors of ATP Citrate Lyase: Structure–Activity Relationship and Inhibition Profiles."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2022 Jan;23(18):10747 49. [IF=3.949] Jiang Anze et al."Effects of Fruit Bagging on the Physiochemical Changes of Grapefruit (Citrus paradisi)."Food Quality and Safety.2022 Jul;: 48. [IF=4.996] Yuan Jie et al."Systematic characterization of the components and molecular mechanisms of Jinshui Huanxian granules using UPLC-Orbitrap Fusion MS integrated with network pharmacology."Scientific Reports.2022 Jul;12(1):1-24 47. [IF=7.514] Jie Meng et al."Conduction of a chemical structure-guided metabolic phenotype analysis method targeting phenylpropane pathway via LC-MS: Ginkgo biloba and soybean as examples."FOOD CHEMISTRY. 2022 Oct;390:133155 46. [IF=5.34] Dong Shao et al."Identification of the active compounds and functional mechanisms of Jinshui Huanxian formula in pulmonary fibrosis by integrating serum pharmacochemistry with network pharmacology."PHYTOMEDICINE. 2022 Jul;102:154177 45. [IF=4.821] Tian Quan et al."Effective extraction methods based on hydrophobic deep eutectic solvent coupled with functional molecularly imprinted polymers: Application on quercetagetin extraction from natural medicine and blood."Microchem J. 2022 Mar;174:107076 44. [IF=4.35] Qian Yu et al."Aged Pericarpium Citri Reticulatae ‘Chachi’ Attenuates Oxidative Damage Induced by tert-Butyl Hydroperoxide (t-BHP) in HepG2 Cells."Foods. 2022 Jan;11(3):273 43. [IF=5.165] Juanning Ren et al."Qualitative and quantitative analysis of multi-components in Xing-Su-Ning Capsules for quality improvement."Arab J Chem. 2022 Jun;15:103825 42. [IF=2.629] Mu Qixuan et al."Study on Closely Related Citrus CMMs based on Chemometrics and Prediction of Components-Targets-Diseases Network by Ingenuity Pathway Analysis."Evid-Based Compl Alt. 2022;2022:1106353 41. [IF=3.361] Yanhui Zhao et al."Rapid characterization of the chemical constituents of Sanhua decoction by UHPLC coupled with Fourier transform ion cyclotron resonance mass spectrometry."Rsc Adv. 2020 Jul;10(44):26109-26119 40. [IF=3.361] Mengmeng Yuan et al."The interaction of dietary flavonoids with xanthine oxidase in vitro: molecular property-binding affinity relationship aspects."Rsc Adv. 2019 Apr;9(19):10781-10788 39. [IF=4.192] Guoyuan Qi et al."Nobiletin Protects against Systemic Inflammation-Stimulated Memory Impairment via MAPK and NF-κB Signaling Pathways."J Agr Food Chem. 2019;67(18):5122–5134 38. [IF=4.411] Liuyi Yu et al."Systematic Detection and Identification of Bioactive Ingredients from Citrus aurantium L. var. amara Using HPLC-Q-TOF-MS Combined with a Screening Method."Molecules. 2020 Jan;25(2):357 37. [IF=4.432] Wei He et al."Flavonoids from Citrus aurantium ameliorate TNBS-induced ulcerative colitis through protecting colonic mucus layer integrity."Eur J Pharmacol. 2019 Aug;857:172456 36. [IF=4.566] Si-wei Wang et al."Nobiletin Alleviates Non-alcoholic Steatohepatitis in MCD-Induced Mice by Regulating Macrophage Polarization."Front Physiol. 2021; 12: 687744 35. [IF=5.279] Konglong Feng et al."Hepatic Lipidomics Analysis Reveals the Antiobesity and Cholesterol-Lowering Effects of Tangeretin in High-Fat Diet-Fed Rats."J Agr Food Chem. 2020;68(22):6142–6153 34. [IF=6.529] Yuqi Ying et al."Pharmacokinetic-Pharmacodynamic Modeling of the Antioxidant Activity of Quzhou Fructus Aurantii Decoction in a Rat Model of Hyperlipidemia."Biomed Pharmacother. 2020 Nov;131:110646 33. [IF=6.922] Ya Wu et al."Preventive Effect of Flavonoid Extract from the Peel of Gonggan (Citrus reticulata Blanco Var. Gonggan) on CCl4-Induced Acute Liver Injury in Mice."J Inflamm Res. 2021; 14: 5111–5121 32. [IF=7.514] Jing Zhao et al."A sensitive and practical ELISA for analyzing naringenin in pummelo and herb samples."Food Chem. 2021 Nov;362:130223 31. [IF=7.514] Yongliang Cui et al."Development of a sensitive monoclonal antibody-based indirect competitive enzyme-linked immunosorbent assay for analysing nobiletin in citrus and herb samples."Food Chem. 2019 Sep;293:144 30. [IF=9.229] Linlin Deng et al."Highly Crystalline Covalent Organic Frameworks Act as a Dual-Functional Fluorescent-Sensing Platform for Myricetin and Water, and Adsorbents for Myricetin."Acs Appl Mater Inter. 2021;13(28):33449–33463 29. [IF=3.046] Menglin Wei et al."Protective effects of a Chotosan Fraction and its active components on β-amyloid-induced neurotoxicity."Neurosci Lett. 2016 Mar;617:143 28. [IF=4.519] Guoyuan Qi et al."Nobiletin protects against insulin resistance and disorders of lipid metabolism by reprogramming of circadian clock in hepatocytes."Bba-Mol Cell Biol L. 2018 Jun;1863:549 27. [IF=4.556] Wei He et al."Citrus aurantium L. and Its Flavonoids Regulate TNBS-Induced Inflammatory Bowel Disease through Anti-Inflammation and Suppressing Isolated Jejunum Contraction."Int J Mol Sci. 2018 Oct;19(10):3057 26. [IF=5.279] Li Liu et al."Structure–Activity Relationship of Citrus Polymethoxylated Flavones and Their Inhibitory Effects on Aspergillus niger."J Agr Food Chem. 2012;60(17):4336–4341 25. [IF=5.548] Ting Wu et al."Antifungal action and inhibitory mechanism of polymethoxylated flavones from Citrus reticulata Blanco peel against Aspergillus niger."Food Control. 2014 Jan;35:354 24. [IF=5.81] Zhang Xianhua et al."Pharmacokinetic Study of 7 Compounds Following Oral Administration of Fructus Aurantii to Depressive Rats."Front Pharmacol. 2018 Mar;0:131 23. Zhang X, Han L, Liu J, et al. Pharmacokinetic Study of 7 Compounds Following Oral Administration of Fructus Aurantii to Depressive Rats. Frontiers in Pharmacology. 2018 ;9:131. DOI: 10.3389/fphar.2018.00131. PMID: 29556193; PMCID: PMC5845165. 22. Wang, Peng, et al. "Chemical and genetic discrimination of commercial Guangchenpi (Citrus reticulata ‘Chachi’) by using UPLC-QTOF-MS/MS based metabolomics and DNA barcoding approaches." RSC advances 9.40 (2019): 23373-23381.https://doi.org/10.1039/C9RA0374 21. Cui, Yongliang, et al. "Development of a sensitive monoclonal antibody-based indirect competitive enzyme-linked immunosorbent assay for analysing nobiletin in citrus and herb samples." Food chemistry 293 (2019): 144-150.https://doi.org/10.1016/j.foodchem.2 20. He, Wei, et al. "Citrus aurantium L. and its flavonoids regulate TNBS-induced inflammatory bowel disease through anti-inflammation and suppressing isolated jejunum contraction." International journal of molecular sciences 19.10 (2018): 3057.https://doi.org 19. He, Wei, et al. "Flavonoids from Citrus aurantium ameliorate TNBS-induced ulcerative colitis through protecting colonic mucus layer integrity." European journal of pharmacology 857 (2019): 172456.https://doi.org/10.1016/j.ejphar.2019.172456 18. Feng, Konglong, et al. "Hepatic lipidomics analysis reveals the antiobesity and cholesterol-lowering effects of tangeretin in high-fat diet-fed rats." Journal of agricultural and food chemistry 68.22 (2020): 6142-6153.https://doi.org/10.1021/acs.jafc.0c017 17. 陳袁,趙倩,康琪,周訓(xùn)美,彭捷.川陳皮素對(duì)非酒精性脂肪肝大鼠降肝脂作用[J].中國(guó)公共衛(wèi)生,2020,36(11):1574-1578. 16. 李榮榮,趙迪,李蒙蒙,舒勝男,王佩陽(yáng),李煥茹,馮素香.基于UHPLC-Q Exactive-Orbitrap高分辨質(zhì)譜研究浙貝母和陳皮主要成分在大鼠體內(nèi)的代謝物[J].藥物分析雜志,2020,40(08):1413-1424. 15. 莉莉,陳勇,張蒙偉,鄢紅霞,高守紅,陳萬(wàn)生.UHPLC-MS/MS法測(cè)定新冠肺炎經(jīng)驗(yàn)方寒濕郁肺湯中11種主成分的含量[J].藥學(xué)實(shí)踐雜志,2021,39(02):148-151+156. 14. 張陽(yáng),姜華茂.川陳皮素對(duì)人前列腺癌DU145細(xì)胞生長(zhǎng)的抑制作用及其機(jī)制[J].吉林大學(xué)學(xué)報(bào)(醫(yī)學(xué)版),2020,46(06):1260-1266+1352. 13. 許守超, 陳屠夢(mèng), 包紹印,等. 基于響應(yīng)面試驗(yàn)設(shè)計(jì)優(yōu)選衢枳殼多指標(biāo)成分工藝研究[J]. 中藥材 2019年42卷11期, 2617-2621頁(yè), MEDLINE ISTIC PKU, 2020. 12. 高俊麗, 邵艷華, 李倩,等. 廣陳皮及其近緣種藥用植物的HPTLC研究[J]. 中國(guó)現(xiàn)代中藥, 2015, 17(010):1020-1025. 11. 謝輝 陳亞 雷愛(ài)玲 等. SPE-HPLC-DAD法同時(shí)檢測(cè)柑橘藥用資源中黃烷酮類和川陳皮素成分[J]. 天然產(chǎn)物研究與開發(fā) 2019(8). 10. 鄧可眾 鄧敏芝 熊英 等. 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質(zhì)檢證書(COA)

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